Transporter DDI – An Evaluation of Approaches and Methodology
- 12 February 2021
- Resource Type: ADME/DMPK, Presentations
Due to an aging population, polypharmacy is increasing. Drug-drug interactions account for 5% of UK hospital admissions, and are a particular concern for common co-meds such as statins.
In this presentation, we focus on:
- a background to drug-drug interactions (DDI)
- the use of the mechanistic static models in the prediction of transporter-mediated DDI
- a comparison of the different published models and their performance
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