Featured in Nature, this article interviews experts, Paul Walker, Rüdiger Fritsch, and Carla Tameling, and provides the latest insights into transcriptomics and how the technology is transforming toxicology prediction.
- an overview of the current challenges in predicting organ-specific toxicity especially DILI
- the advantages of using human cell-based models with a particular focus on 3D organoid models
- a background to transcriptomics and how advances in throughput have widened its application
- how combining transcriptomics with machine learning and artificial intelligence has increased the power of this technology in toxicology prediction