Science Pool

Purkinje cells firing recorded by a high density multi-electrode array: a new tool for compounds validation

This poster includes information about:

  • Functional brain slice electrophysiology by HD-MEA platform
  • Combined neuronal circuitry studies through functional brain tissue imaging

Initially presented at FENS 2018 by Ugolini et al., 3Brain high-density multi electrode array (HD-MEA) as a system for long lasting monitor and characterize spiking activity of hundreds Purkinje cells simultaneously by using different positive and negative Ca++-activated K+ channels. Responses can be evaluated though different analysis. It is a useful tool for compounds validation on cerebellar slices.