Science Pool

Prediction of Functional and Structural Cardiotoxicants using hiPSC Cardiomyocytes

Cardiotoxicity remains one of the most reported adverse drug reactions that lead to drug attrition during pre-clinical and clinical drug development. Drug-induced cardiotoxicity may develop as a functional change in cardiac electrophysiology (acute alteration of the mechanical function of the myocardium) and/or as a structural change, resulting in loss of viability and morphological damage to cardiac tissue.

Our latest work, published in Expert Opinion on Drug Metabolism & Toxicology, is now available to download.

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