PKPD Models for Antibiotic Efficacy
- 15 February 2021
- Resource Type: In vivo Pharmacology, Posters
Pharmacokinetic/pharmacodynamic (PK/PD) modelling plays an important role in drug development, especially in the case of antibiotics where the data generated is used for dose prediction up to Phase 2 clinical trials. This enables efficient study designs and identification of optimal dosing regimens that may suppress drug resistance.
In this poster, we focus on:
- mathematical modelling of in vivo and in vitro data to generate a rational design with reduced animal requirements in order to determine the pharmacodynamic driver and magnitude of antibiotic efficacy
- optimisation of the clinical dose regimen in Phase 2 clinical trials
Read our poster to learn more about our research!
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