Pilocarpine is a muscarinic receptor agonist, originally developed to treat dry mouth and glaucoma. It is also used to induce epilepsy in the rat.
In this poster, we focus on:
pilocarpine response in vitro using MEA
analysis of the neuronal responses of different cell types such as cryopreserved rat cortical neurons, rat hippocampal neurons and human iPSC-derived glutamatergic neurons and astrocytes
the impact of cell maturation (DIV)
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