Mechanisms of Drug-induced Toxicity Guide
- 16 February 2021
- Resource Type: Guides, Toxicology & Safety
Our popular, easy-to-follow guide: ‘Mechanisms of Drug-induced Toxicity’ is available to read online.
Read about:
- an overview of the different mechanisms of toxicity including:
- mitochondrial toxicity
- reactive oxygen species (ROS) and oxidative stress
- reactive metabolite formation
- cell cycle mediated toxicity
- apoptosis
- genotoxic and non-genotoxic carcinogens
- phospholipidosis
- steatosis
- cholestasis
- cardiac ion channel effects and hypertrophy
- an assessment of the current in vitro methods available for determining mechanistic toxicology
- key references and further reading related to the topic
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