In Vitro 3D Heart – Microtissue Model for Understanding Cardiotoxicity
- 11 February 2021
- Resource Type: Posters, Toxicology & Safety
In vitro 3D microtissue models are transforming our understanding of cardiotoxicity.
In this poster, we focus on:
- the use of a 3D cardiac triculture model consisting of iPSC-derived cardiomyocytes, cardiovascular endothelial cells and cardiac fibroblasts in cardiotoxicity prediction
- the detection of functional and structural mechanisms of cardiotoxicity
- calcium flux as a sensitive detection method for cardiac contraction as well as microtissue area for identifying cardiac hypertrophy
- HCS detection of cell health markers such as mitochondrial function, calcium homeostasis and nuclei/DNA structure
Read our poster to learn more about our research!
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