Improving the Prediction of Mitochondrial Toxicity
- 7 March 2021
- Resource Type: Articles & Whitepapers, Toxicology & Safety
Drug-induced mitochondrial dysfunction has been associated with organ toxicity and drug withdrawal. Highly specific and sensitive in vitro assays have been developed to predict mitochondrial dysfunction.
In this publication, we focus on:
- a background to mitochondrial toxicity
- a comparison of the Glu/Gal mitochondrial assay with the Seahorse assay for the prediction of mitochondrial toxicity
- how the Seahorse assay provides a mechanistic understanding of mitochondrial toxicity
Read our publication to learn more!
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