Science Pool

Ensuring Bioanalytical Quality in a Highly Automated HT-ADME Laboratory

The field of high-throughput ADME (HT-ADME) places a greater demand on the analytical systems supplying end point quantification.

In this review, we focus on:

  • recent technological advances in LC–MS/MS which dramatically reduce sample analysis time
  • evaluating the impact of reduced sample analysis time on analytical data quality
  • the use of appropriate LC-MS/MS systems
  • software tools to aid bioanalytical quality

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