ADME/DMPK, Articles & Whitepapers, Immunology & Inflammation, In vitro Biology, Medicinal Chemistry Filling a nick in NIK 21 June 2023 Learn more
Blog, Medicinal Chemistry, Posters Sustainability and Green Chemistry at Evotec 14 November 2022 Learn more
Blog, Formulation & CMC, IND Enabling Studies/Preclinical Development, Medicinal Chemistry, Toxicology & Safety Expansion of the medium scale Oligonucleotides manufacture capabilities at Campus Levi-Montalcini in Verona 19 October 2022 Learn more
Articles & Whitepapers, Medicinal Chemistry, Neuroscience, Structural Biology & Protein Science Structural Basis of SARM1 Activation, Substrate Recognition, and Inhibition by Small Molecules 29 March 2022 Learn more
Articles & Whitepapers, Medicinal Chemistry, Proteomics, Metabolomics & Biomarkers Development of a Ligand for In Vivo Imaging of Mutant Huntingtin in Huntington’s Disease 10 March 2022 Learn more
Anti-Infectives, Articles & Whitepapers, Medicinal Chemistry In Vitro and In Vivo Inhibition of the Mycobacterium tuberculosis 11 February 2022 Learn more
Articles & Whitepapers, crystallography, Medicinal Chemistry, Neuroscience SARM1a Metabolic Sensor Activated by Increased NMN/NAD+ Ratio to Trigger Axon Degeneration 11 January 2022 Learn more
Anti-Infectives, Articles & Whitepapers, Immunology & Inflammation, In vitro Biology, Medicinal Chemistry Integrative Analysis of Human Macrophage Inflammatory Response Related to Mycobacterium Tuberculosis Virulence 11 January 2022 Learn more
Age-Related Diseases, Articles & Whitepapers, In vitro Biology, Medicinal Chemistry, Neuroscience Discovery of Pyrazolo[1,5-a]pyrazin-4-ones as Potent and Brain Penetrant GluN2A-Selective Positive Allosteric Modulators Reducing AMPA Receptor Binding Activity 22 December 2021 Learn more
Articles & Whitepapers, crystallography, epigenetics, Medicinal Chemistry, Oncology, SBDD Small-Molecule Inhibition of METTL3 as a Strategy Against Myeloid Leukaemia 21 December 2021 Learn more
ADME/DMPK, Anti-Infectives, Antibacterial, Antimicrobial resistance, Articles & Whitepapers, In vitro Biology, In vivo Pharmacology, Medicinal Chemistry Discovery of Novel UDP-N-Acetylglucosamine Acyltransferase (LpxA) Inhibitors 30 September 2021 Learn more
Anti-Infectives, Articles & Whitepapers, Medicinal Chemistry Novel Glycerophospholipid, Lipo- and N-acyl Amino Acids from Bacteroidetes: Isolation, Structure Elucidation and Bioactivity 31 August 2021 Learn more
![Discovery of Pyrazolo[1,5-a]pyrazin-4-ones as Potent and Brain Penetrant GluN2A-Selective Positive Allosteric Modulators Reducing AMPA Receptor Binding Activity](https://sciencepool.evotec.com/wp-content/uploads/elementor/thumbs/shutterstock_1306602358-neuron-pink-03-science-pool-scaled-qcs34q8ris3z3a1zrw8a2wi26nqnao7ylhwzn79yzg.jpg "Discovery of Pyrazolo[1,5-a]pyrazin-4-ones as Potent and Brain Penetrant GluN2A-Selective Positive Allosteric Modulators Reducing AMPA Receptor Binding Activity")
