Articles & Whitepapers, crystallography, Medicinal Chemistry, Neuroscience SARM1a Metabolic Sensor Activated by Increased NMN/NAD+ Ratio to Trigger Axon Degeneration 11 January 2022 Learn more
Anti-Infectives, Articles & Whitepapers, Immunology & Inflammation, In vitro Biology, Medicinal Chemistry Integrative Analysis of Human Macrophage Inflammatory Response Related to Mycobacterium Tuberculosis Virulence 11 January 2022 Learn more
Anti-Infectives, Articles & Whitepapers, In vivo Pharmacology Cyclohexyl-Griselimycin is Active Against Mycobacterium Abscessus in Mice 11 January 2022 Learn more
Articles & Whitepapers, Biologics An Improved Protocol for Automated Multi-Attribute Method Sample Preparation 5 January 2022 Learn more
Age-Related Diseases, Articles & Whitepapers, In vitro Biology, Medicinal Chemistry, Neuroscience Discovery of Pyrazolo[1,5-a]pyrazin-4-ones as Potent and Brain Penetrant GluN2A-Selective Positive Allosteric Modulators Reducing AMPA Receptor Binding Activity 22 December 2021 Learn more
Articles & Whitepapers, In vivo Pharmacology, Respiratory Mouse Pneumonia Model by Acinetobacter baumannii Multidrug Resistant Strains 21 December 2021 Learn more
Articles & Whitepapers, crystallography, epigenetics, Medicinal Chemistry, Oncology, SBDD Small-Molecule Inhibition of METTL3 as a Strategy Against Myeloid Leukaemia 21 December 2021 Learn more
Articles & Whitepapers, Biologics, In vitro Biology Recombinase-based Targeted Integration Systems for Exogenous Protein Production 14 December 2021 Learn more
Articles & Whitepapers, Structural Biology & Protein Science Structure-Based Virtual Screening: Fine Tuning for Success 26 November 2021 Learn more
Articles & Whitepapers, Hit & Target ID/Validation User Friendly Quantum Mechanics and Applications in Drug Discovery 26 November 2021 Learn more
Articles & Whitepapers, Proteomics, Metabolomics & Biomarkers, Toxicology & Safety Machine Learning using Omics Data 26 November 2021 Learn more
![Discovery of Pyrazolo[1,5-a]pyrazin-4-ones as Potent and Brain Penetrant GluN2A-Selective Positive Allosteric Modulators Reducing AMPA Receptor Binding Activity](https://sciencepool.evotec.com/wp-content/uploads/elementor/thumbs/shutterstock_1306602358-neuron-pink-03-science-pool-scaled-pjjlyep8mot7b75e0xh4w5m9xszqtdspx8dvsaz4nw.jpg "Discovery of Pyrazolo[1,5-a]pyrazin-4-ones as Potent and Brain Penetrant GluN2A-Selective Positive Allosteric Modulators Reducing AMPA Receptor Binding Activity")
