Date: 27 February – 2 March 2023
Venue: San Diego, CA
Attendees:
- Cris Cable, Director Automation in Manufacturing Technical Operations at Just – Evotec Biologics
- Anna Klug, Scientist at Just – Evotec Biologics
Join us in-person in San Diego or online for BioProcess International US West where Just – Evotec Biologics will be presenting.
Presentation | 28 February from 4:30 – 5:00pm PST
Flexible Automation to Achieve Continuous Bioprocess Manufacturing
The success of low-cost, high quality biopharmaceutical manufacturing relies on the Process Automation System, a cornerstone to Just – Evotec Biologics’ continuous manufacturing platform. This presentation will discuss the four pillars on which the automation platform was developed: (a) reconfigurability of equipment in the process train, (b) flexibility to select custom-built or commercially available process equipment, (c) management of volumes and flow control across the continuous process, and (d) custom-designing recipe sequences to drive control of the continuous unit operations. The Process Automation System supports both Hybrid (partially-connected) and End-to-End (E2E) continuous bioprocesses at up to 1000L scale, with E2E having been demonstrated at the 500L scale.
Presented by Cris Cable, Director Automation in Manufacturing Technical Operations at Just – Evotec Biologics
Presentation | 28 February from 4:30 – 5:00pm PST
Inducible Systems for Recombinant Protein Expression in CHO CellsS
To reduce the cost of recombinant protein therapeutics, significant focus has been placed on increasing cellular productivity. Higher levels of expression however increase metabolic burden and inhibit growth and cell line stability, especially if the molecule is toxic. At Just-Evotec Biologics, we have developed an inducible expression system in CHO cells to enable induction of protein expression to reduce metabolic burden and limit the effects of expressing toxic therapeutic proteins, resulting in overall higher expression.
Presented by Ana Klug, Scientist at Just – Evotec Biologics
If you wish to meet with us in San Franciso, get in touch via the form below, we will be happy to arrange a meeting.
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