During analysis of samples from HT-ADME screening, non-specific binding can cause challenges due to accumulation within the analytical system. This can result in poor peak shape, low sensitivity, increasing back pressure/pressure spikes, carryover or system clogging.
In this poster, we focus on:
the evaluation of the WatersTM Acquity Premier UPLC in conjunction with the Acquity Premier HSS T3 column technology which contain an inert coating specifically formulated to eliminate analyte/surface interactions
a comparison with standard UPLC technology
details on the benefits of using the Waters AcquityTM system in terms of chromatographic performance and sensitivity
Read our poster to learn more about our research!
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